New and existing policy response options can be evaluated by GLOBIO, mostly in combination with other models such as IMAGE or CLUE. GLOBIO analyzes the potential effectivity of options assuming full implementation. Consequently, different options can be compared.

For example, the following policy response options were explored for the second Global Biodiversity Outlook (see also the report Cross-roads of Life on Earth):
GLOBIO can be used to analyze global policy options, but also options at regional and national scales. An example is the implementation of networks of protected areas.